Receptor-Deficient Mice and Alters Aortic Gene Expression Determined by Microarray Maternal Hypercholesterolemia During Pregnancy Promotes Early Atherogenesis in LDL
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چکیده
Claudio Napoli, Filomena de Nigris, John S. Welch, Federico B. Calara, Robert O. Stuart, Receptor-Deficient Mice and Alters Aortic Gene Expression Determined by Microarray Maternal Hypercholesterolemia During Pregnancy Promotes Early Atherogenesis in LDL Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/hc1102.106792 2002;105:1360-1367 Circulation. http://circ.ahajournals.org/content/105/11/1360 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray.
BACKGROUND Maternal hypercholesterolemia during pregnancy is associated with markedly enhanced fatty streak formation in human fetal aortas and accelerated progression of atherosclerosis in normocholesterolemic children. METHODS AND RESULTS To establish the causal role of maternal hypercholesterolemia in a genetically homogeneous murine model and to test the hypothesis that pathogenic events ...
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